Hmmmmm...
For the armor node, I think a team comp of Dead of Winter, Private Dick and Last Hope would be difficult to take on. 2 fighters that are supposed to make you waste time on taking them out take even longer to take out, those being DoW and Last Hope. Meanwhile PD's already very tanky and his 50/50 chance of resisting a debuff can make him a very difficult fighter to deal meaningful damage to with bleed or something. Last Hope supporting them only makes things harder. Another good comp would be Heavy Metal, Brain Freeze, and Sketchy. Heavy Metal and Brain Freeze can tank while Sketchy makes them immune to bleeds and armor break while also letting them gain meter faster.
For the immunity node, fighters like G.I Jazz, Meow and Furever, Armed Forces, and Resonant Evil become monsters since your methods of defeating them become very limited. Bleed and armor break all become worthless because of immunity.
For the boss node, there are several comps that I feel could become problematic. One in particular I feel that way towards would be Resonant Evil, Buzzkill with Grudge, and Surgeon General. Another one would be Bio-Exorcist, Dread Locks, and Armed Forces. Immoral would work excellently there too. The massive health boost on that node would make her too risky to take on without hex or killing her last.